BDBM50577297 CHEMBL4851439
SMILES FC(F)c1cncc(c1)-c1ccc2ncc3nnc(C4=CCCOCC4)n3c2c1
InChI Key InChIKey=ATKHYZXUMVNCIO-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50577297
Affinity DataIC50: 81nMAssay Description:Inhibition of DNA-PK (unknown origin) using biotin-PEG2-TWSLPLSQDSASE-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of DNA-PK in human HT-144 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair